Predictive factors of large liver cell carcinoma tumor response after first conventional transarterial chemoembolization in Indonesia according to the modified response evaluation in solid tumors criteria: a preliminary study

Background: Various factors affect the response of large hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE), and high demand for TACE procedures highlights need information methods on criteria patient selection. Methods: Thirty-six HCC patients who were treated with conventional between January 2014 2020 had pre- postoperative imaging data included in analysis. The categorized as tumor responders (complete or partial response) nonresponders (stable progressive disease) according to modified evaluation solid tumors (mRECIST). Eight predictive (Tumor diameter, Tumor amount, vascularity, portal vein invasion, location, presence capsule, Child–Pugh class, alpha-fetoprotein (AFP) level) evaluated using multivariate analysis logistic regression. Results: Only 42% fell into category TACE. None class B showed a response. A group that lesion diameter 5–10 cm (OR: 8.78, 95% CI: 1.73–44.55; P = 0.009) are an independent predictor first procedure. Conclusions: could be use patients, further researches needed confirm this finding.